Author

Tharindu A. Ranathunge

St. Jude Children's Research HospitalORCID 0000-0002-1152-6679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Lei YangiD· 2 shared Anang A. ShelatiD· 1 shared Bohyeon JeongiD· 1 shared J. WangiD· 1 shared Mary Ashley RimmeriD· 1 shared Nathaniel R. TwarogiD· 1 shared Taosheng CheniD· 1 shared Yong LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Lei YangORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 5, 2026

Benzopyrene-induced AHR activation in human ESCs primes premature neurogenesis in brain organoids

Bohyeon Jeong, Lei Yang, Tharindu A. Ranathunge, Young-Goo Han

This study shows that BaP exposure of human ESCs before organoid generation causes premature neurogenesis and morphological defects, which can be reversed by AHR inhibition.

DOI 10.64898/2026.04.30.722088

humanbulk RNA-seq

BiochemistryAnalytical ChemistryPeer-reviewedSep 12, 2025

rtmsEcho: An Open-Source R Package for Automated Analysis of Acoustic Ejection Mass Spectrometry Data

Mary Ashley Rimmer, Nathaniel R. Twarog, Tharindu A. Ranathunge…·Lei Yang

rtmsEcho automates AEMS data processing tasks like peak detection and multimodal analysis, improving efficiency in high-throughput applications.

2 citations

metabolomicsdeep learning