ImmunologybioRxivPreprint
A systematic approach to understanding how patient variants affect the activity of Wiskott-Aldrich syndrome protein
Lia Gonçalves Pinho, Marcus Rafael Bezerra, Axel Leppert…·Lisa S. Westerberg
This paper systematically analyzes how patient variants affect WASp activity, identifying gain-of-function and loss-of-function variants through structural and functional assays.
DOI 10.64898/2026.05.19.726146