Ann Marie Egloff

This study identifies high-avidity TCR signaling via NFAT as a key driver of NKG2A-positive CD8 T cell exhaustion in human tumors, with implications for immunotherapy.

This study shows that a cancer vaccine combined with anti-PD-1 therapy reduces tumor burden and improves survival in a head and neck cancer model with impaired T cell responses.

7-UP generates in silico 40-plex CODEX data from a 7-plex mIF panel using cellular morphology, enabling cell type classification and survival prediction across diverse samples.

SPACE-GM identifies spatial motifs in cancer samples linked to recurrence and immunotherapy outcomes using geometric deep learning.