BioinformaticsNucleic Acids ResearchPeer-reviewed
Deep learning of the splicing (epi)genetic code reveals a novel candidate mechanism linking histone modifications to ESC fate decision
Yungang Xu, Yongcui Wang, Jiesi Luo…·Xiaobo Zhou
The paper introduces DeepCode, a deep learning model that integrates epigenetic features to predict splicing patterns during hESC differentiation and identifies a novel mechanism linking histone modifications to cell fate decisions.
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