Mind the Gap: Does Brain Age Improve Alzheimer's Disease Prediction?
Trevor Wei Kiat Tan, Kim‐Ngan Nguyen, Chen Zhang, Ru Kong, Susan F Cheng, Fang Ji, Joanna Su Xian Chong, Eddie Jun Yi Chong, Narayanaswamy Venketasubramanian, Csaba Orbán, Michael W.L. Chee, Christopher Chen, Juan Helen Zhou, B.T. Thomas Yeo, The Alzheimer's Disease Neuroimaging Initiative, The Australian Imaging Biomarkers and Lifestyle Study of Aging
This study compares brain age models and direct models for predicting Alzheimer's Disease outcomes, finding that direct models perform better despite brain age models having larger training data.
Human Brain Mapping · Aug 15, 2025Peer-reviewedNeuroscience