Molecular BiologybioRxivPreprint
TFU72 is a novel and potent DNA-PKcs inhibitor for enhancing homology-directed repair gene editing
Sridhar Selvaraj, Ludwig Schmiderer, Jacob Lamberth…·Matthew Hebden Porteus
The paper introduces TFU72, a potent DNA-PKcs inhibitor that significantly enhances HDR gene editing efficiency while mitigating genotoxic side effects.
DOI 10.64898/2026.03.10.710954