Author

Guy Yealland

University of FreiburgORCID 0000-0002-1216-4091Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amr Al‐ShebeliD· 1 shared Annika FendleriD· 1 shared Bernhard RallaiD· 1 shared Carlos Cordero OropezaiD· 1 shared Dimitra PapaioannouiD· 1 shared Emily Haar· 1 shared Jan HalbritteriD· 1 shared Kai‐Uwe EckardtiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Amr Al‐ShebelORCID

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1 paper

Recent·Most cited

Base Editing as a Therapeutic Strategy for Autosomal Dominant Tubulointerstitial Kidney Disease caused by Pathogenic UMOD Variants

Nora Diederich, Sarah Wendlinger, Shuhan Kong, Dimitra Papaioannou, Emily Haar, Amr Al‐Shebel, Guy Yealland, Wenjun Jin, Carlos Cordero Oropeza, Ria Anne-Rose Schönauer, Roberta Di Costanzo, Marta Mariniello, Annika Fendler, Bernhard Ralla, Kai‐Uwe Eckardt, , Michael M. Kaminski

This paper evaluates base editing strategies for treating ADTKD-UMOD by correcting pathogenic UMOD variants and inactivating mutant alleles, showing efficient correction and expression modulation in cell models.

bioRxiv · Oct 16, 2026 · PreprintGenetics