Developmental BiologybioRxivPreprint
Limitations in PPAR-dependent mitochondrial programming restrain the differentiation of human stem cell-derived β cells
Anne C. Lietzke, Emily M. Walker, Elizabeth J. Bealer…·Scott A. Soleimanpour
This study identifies PPAR-dependent mitochondrial programming as a limiting factor in the differentiation of human stem cell-derived β cells and shows that PPAR agonists can enhance β cell formation and function.
4 citations