Author

Elizabeth J. Bealer

University of MichiganORCID 0000-0001-6767-4091Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Lonnie D. SheaiD· 2 shared Aaron H. MorrisiD· 1 shared Amod TalekariD· 1 shared Anne C. LietzkeiD· 1 shared Antonio Louis A. Holmes· 1 shared Ava M. Stendahl· 1 shared Bae-Jin HaiD· 1 shared Belle A. Henry-Kanarek· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

Lonnie D. SheaORCID

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2 papers

Recent·Most cited

Synthetic Immunological Niche Reveals Early Immune Dysregulationand Stratifies Therapeutic Response in Type 1 Diabetes

Jyotirmoy Roy, Yifei Jiang, Runbo Mao, Jessica L. King, Amod Talekar, Lillian Page Holman, Haoxuan Zeng, Xin Luo, Peter Sajjakulnukit, Bae-Jin Ha, Kai Liu, Elizabeth J. Bealer, Laila M. Rad, Shahzad Sohail, Antonio Louis A. Holmes, , Lonnie D. Shea

The paper develops a synthetic immunological niche to identify early immune dysregulation and stratify therapeutic response in Type 1 Diabetes.

bioRxiv · Mar 10, 2026 · PreprintBioengineering

Limitations in PPAR-dependent mitochondrial programming restrain the differentiation of human stem cell-derived β cells

Anne C. Lietzke, Emily M. Walker, Elizabeth J. Bealer, Kelly M. Crumley, Jessica King, Ava M. Stendahl, Jie Zhu, Gemma L. Pearson, Elena Levi-D’Ancona, Belle A. Henry-Kanarek, Rebecca K. Davidson, Jin Li, Emma C. Reck, Yifei Wu, Manikanta Arnipalli, , Scott A. Soleimanpour

This study identifies PPAR-dependent mitochondrial programming as a limiting factor in the differentiation of human stem cell-derived β cells and shows that PPAR agonists can enhance β cell formation and function.

bioRxiv · Jul 26, 2024 · PreprintDevelopmental Biology