Author

Michael Spedding

ORCID 0000-0002-1248-8221Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexandre HenriquesiD· 1 shared Bradley J. TurneriD· 1 shared Jean‐Philippe LoeffleriD· 1 shared Shyuan Thieu NgoiD· 1 shared Sophia J. LuikingaiD· 1 shared Thusi Rapasinghe· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperNeuroscience

Alexandre HenriquesORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintAug 30, 2022

Profound lipid dysregulation in mutant TDP-43 mice is ameliorated by the glucocerebrosidase 2 inhibitor ambroxol

Sophia J. Luikinga, Alexandre Henriques, Shyuan Thieu Ngo…·Bradley J. Turner

This study identifies lipid dysregulation in TDP-43 mutant mice and shows ambroxol improves motor function and preserves neurons by modulating glycosphingolipid metabolism.

4 citations

mousestatistical model

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