Author

Sophia J. Luikinga

The University of MelbourneORCID 0000-0001-5058-3281Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Bradley J. TurneriD· 2 shared A. ColeiD· 1 shared Aida Viden· 1 shared Alexandre HenriquesiD· 1 shared Brittany CuiciD· 1 shared Catriona McLeaniD· 1 shared David G. GonsalveziD· 1 shared Doris TomasiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Bradley J. TurnerORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 30, 2022

Profound lipid dysregulation in mutant TDP-43 mice is ameliorated by the glucocerebrosidase 2 inhibitor ambroxol

Sophia J. Luikinga, Alexandre Henriques, Shyuan Thieu Ngo…·Bradley J. Turner

This study identifies lipid dysregulation in TDP-43 mutant mice and shows ambroxol improves motor function and preserves neurons by modulating glycosphingolipid metabolism.

4 citations

mousestatistical model

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 13, 2021

Cortical hyperexcitability drives dying forward ALS symptoms and pathology in mice

Mouna Haidar, Aida Viden, Brittany Cuic…·Bradley J. Turner

This study shows that cortical hyperexcitability in mice leads to ALS-like motor symptoms and pathology through a dying-forward mechanism.

6 citations

mouseexperimental assay

𝕏 PostBluesky