ImmunologyNature CommunicationsPeer-reviewed
✦ In-depth digest
A Paradoxical Tumor Antigen Specific Response in the Liver
Rajiv Trehan, Patrick Huang, Xiao Bin Zhu…·Tim F. Greten
Liver tumors in mice and patients hold many tumor-specific CD8+ T cells that are exhausted; SPP1+ macrophages and a liver-specific intermediate macrophage population are linked to this dysfunction.