Author

Tim F. Greten

National Institutes of HealthORCID 0000-0002-0806-2535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Firouzeh KorangyiD· 2 shared Mohamed-Reda BenmebarekiD· 2 shared Patrick HuangiD· 2 shared Xiao Bin Zhu· 2 shared Alexander KroemeriD· 1 shared Amran Nur· 1 shared Chi Ma· 1 shared Chi MaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Firouzeh KorangyORCID

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2 papers

Recent·Most cited

Engineering CAR T Cells for Hepatocellular Carcinoma Recurrence after Liver Transplantation

Lorenz Kocheise, Gabriel Prata Bacil, Pavan Bhimalli, Mohamed-Reda Benmebarek, D J Li, Patrick Huang, Chi Ma, Vinona Muralidaran, Jorge Humberto Hernández-Félix, Joseph R. Bugliarelli, Raj Chari, Kylynda C. Bauer, Yuta Myojin, Sarah Firdaus, Xiao Bin Zhu, , Tim F. Greten

This paper develops GPC3-targeted CAR T cells resistant to immunosuppressive drugs and with reduced alloreactivity, showing efficacy in preclinical models and feasibility for clinical use post-liver transplantation.

bioRxiv · Jul 5, 2026 · PreprintImmunology

A Paradoxical Tumor Antigen Specific Response in the Liver

Rajiv Trehan, Patrick Huang, Xiao Bin Zhu, Xin Wang, Marlaine Soliman, Dillon Strepay, Amran Nur, Noémi Kedei, Martin Arhin, Shadin Ghabra, Francisco Rodríguez-Matos, Mohamed-Reda Benmebarek, Chi Ma, Firouzeh Korangy, Tim F. Greten

Liver tumors in mice and patients hold many tumor-specific CD8+ T cells that are exhausted; SPP1+ macrophages and a liver-specific intermediate macrophage population are linked to this dysfunction.

Nature Communications · May 7, 2025Peer-reviewedImmunology✦ In-depth digest