Author

Deena Iskander

Imperial College LondonORCID 0000-0002-1278-3888Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:statistical model· 2 Approach:transformer / foundation model· 2

Frequent Co-Authors

Anindita RoyiD· 4 shared Irene A. G. RobertsiD· 4 shared Amirhossein VahidiiD· 2 shared April Rose FosteriD· 2 shared Ash HollandiD· 2 shared Berthold GöttgensiD· 2 shared Bethan PsailaiD· 2 shared Daniela Basurto-LozadaiD· 2 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersBioinformatics

Anindita RoyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologyBloodPeer-reviewedMay 29, 2026

The fetal specific gene LIN28B is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia

Rebecca E. Ling, Alia M. N. Welsh, Lucy Hamer…·Anindita Roy

This study identifies LIN28B as essential for fetal B-lymphopoiesis and KMT2A::AFF1 infant leukemia initiation, showing its role in promoting proliferation and leukemogenesis.

3 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 26, 2026

Self-supervised learning for a gene program-centric view of cell states

Marie Moullet, Tomoya Isobe, Amirhossein Vahidi…·Mohammad Lotfollahi

Tripso, a self-supervised transformer model, identifies gene program-specific embeddings and discovers novel gene programs, revealing biological insights in hematopoietic development and disease.

DOI 10.64898/2026.03.24.713961

humanscRNA-seq

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BioinformaticsbioRxivPreprintMar 5, 2026

Predicting how perturbations reshape cellular trajectories with PerturbGen

Kevin Chi Hao Ly, Adib Miraki Feriz, Tomoya Isobe…·Mohammad Lotfollahi

PerturbGen predicts how genetic perturbations affect cellular trajectories across time in human datasets, showing effects on immune responses, hematopoiesis, and skin development.

DOI 10.64898/2026.03.04.709254

humanscRNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintApr 20, 2021

Developmental stage- and site-specific transitions in lineage specification and gene regulatory networks in human hematopoietic stem and progenitor cells

Anindita Roy, Guanlin Wang, Deena Iskander…·Supat Thongjuea

This study identifies site- and stage-specific transitions in gene regulatory networks and lineage specification in human hematopoietic stem and progenitor cells across developmental stages.

DOI 10.1101/2021.04.20.440420

humanscRNA-seq

𝕏 PostBluesky