Author

Thea Brennan-Krohn

Beth Israel Deaconess Medical CenterORCID 0000-0002-1284-0643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Abigail L. MansoniD· 2 shared Ashlee M. EarliD· 2 shared Aimee Iradukunda· 1 shared Alejandro PirontiiD· 1 shared Andrew Bruce OnderdonkiD· 1 shared Bruce J. Walker· 1 shared Cassiana E. BittencourtiD· 1 shared Christina A. CuomoiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMicrobiology

Abigail L. MansonORCID

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2 papers

Recent·Most cited

Rapid Emergence of Resistance to Broad-Spectrum Direct Antimicrobial Activity of Avibactam

Michelle Naegeli, Shade Rodriguez, Aimee Iradukunda, Abigail L. Manson, Ashlee M. Earl, Thea Brennan-Krohn

This study shows avibactam resistance emerges rapidly through a large mutational target, with no significant growth rate difference between resistant and susceptible strains.

Microbiology Spectrum · Jun 12, 2025Peer-reviewedMicrobiology

Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance

Rauf Salamzade, Abigail L. Manson, Bruce J. Walker, Thea Brennan-Krohn, Colin J. Worby, Peijun Ma, Lorrie L. He, Terrance Shea, James Qu, Sinéad B. Chapman, Whitney Howe, Sarah Young, Jenna I. Wurster, Mary Louise Delaney, Sanjat Kanjilal, , Ashlee M. Earl

The paper develops a method to trace horizontal gene transfer and persistence of carbapenem resistance genes across bacterial species using genomic data from clinical isolates.

Genome Medicine · Apr 4, 2022Peer-reviewedGenomics