Author

Bruce J. Walker

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:variant calling· 3 Assay:whole-genome sequencing· 2 Research Focus:clustering· 1 Research Focus:deconvolution· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

Abigail L. MansoniD· 3 shared Ashlee M. EarliD· 3 shared Christine AnyansiiD· 2 shared Colin J. WorbyiD· 2 shared Thomas AbeeliD· 2 shared Timothy J. StraubiD· 2 shared Alejandro PirontiiD· 1 shared Alexandra GroteiD· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenomics

Abigail L. MansonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance

Rauf Salamzade, Abigail L. Manson, Bruce J. Walker, Thea Brennan-Krohn, Colin J. Worby, Peijun Ma, Lorrie L. He, Terrance Shea, James Qu, Sinéad B. Chapman, Whitney Howe, Sarah Young, Jenna I. Wurster, Mary Louise Delaney, Sanjat Kanjilal, , Ashlee M. Earl

The paper develops a method to trace horizontal gene transfer and persistence of carbapenem resistance genes across bacterial species using genomic data from clinical isolates.

Genome Medicine · Apr 4, 2022Peer-reviewedGenomics

StrainGE: A toolkit to track and characterize low-abundance strains in complex microbial communities

Lucas R. van Dijk, Bruce J. Walker, Timothy J. Straub, Colin J. Worby, Alexandra Grote, Henry L. Schreiber, Christine Anyansi, Amy J. Pickering, Scott J. Hultgren, Abigail L. Manson, Thomas Abeel, Ashlee M. Earl

StrainGE identifies low-abundance microbial strains from metagenomic data with higher sensitivity and resolution than existing tools.

Genome biology · Mar 7, 2022Peer-reviewedBioinformatics

QuantTB - A method to classify mixed Mycobacterium tuberculosis infections within whole genome sequencing data

Christine Anyansi, Arlin Keo, Bruce J. Walker, Timothy J. Straub, Abigail L. Manson, Ashlee M. Earl, Thomas Abeel

QuantTB classifies mixed Mycobacterium tuberculosis infections in whole genome sequencing data, accurately quantifying strains and detecting resistance mutations.

BMC Genomics · Jan 28, 2020Peer-reviewedGenomics