WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus
Jiahui Liu, Chatrawee Duangjan, Ronald W. Irwin, Sean P. Curran
This study shows that loss of WDR23 in mice leads to increased NRF2 stability and antioxidant defense, affecting age-related hippocampal behaviors in sex-dependent ways.
Mechanisms of Ageing and Development · Apr 1, 2024Peer-reviewedMolecular Biology