Cell State Chaos Underpins the Evolution of SMARCA4-Deficient Dedifferentiated Endometrial Cancer
Mackenzie Brandon‐Coatham, Julia Avian Vassalakis, Hannah Plummer…·Lynne-Marie M Postovit
This study shows that SMARCA4 loss in endometrial cancer leads to cell state chaos, not stemness, causing dedifferentiation through epigenomic dysregulation.