Molecular BiologybioRxivPreprint
Lysine-rich regions located in the C-terminal domain of DNA Topoisomerase 2-alpha act as polyphosphoinositide interaction sites and nucleolar localisation signals
Vandana V. Ardawatia, Rhîan G. Jacobsen, Diana Cornelia Turcu…·Aurélia E. Lewis
The paper identifies lysine-rich regions in TOP2A's C-terminal domain as PPIn interaction sites and nucleolar localisation signals, showing their role in nuclear PPIn dynamics.
DOI 10.1101/2025.01.29.635480