Author

Tianshi Lu

The University of Texas Southwestern Medical CenterORCID 0000-0002-1344-866XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:Bayesian inference· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Hao ZhuiD· 1 shared James BrugarolasiD· 1 shared James J. ZhuiD· 1 shared Jason J. LukeiD· 1 shared Jianjun GaoiD· 1 shared Laurentiu M. PopiD· 1 shared Lin XuiD· 1 shared Mingyi CheniD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Hao ZhuORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tumor Neoantigenicity Assessment with CSiN Score Incorporates Clonality and Immunogenicity to Predict Immunotherapy Outcomes

Tianshi Lu, Shidan Wang, Lin Xu, Qinbo Zhou, Nirmish Singla, Jianjun Gao, Subrata Manna, Laurentiu M. Pop, Zhiqun Xie, Mingyi Chen, Jason J. Luke, James Brugarolas, Raquibul Hannan, Tao Wang

The paper introduces the CSiN score to predict immunotherapy outcomes by assessing tumor neoantigen quality through clonality and immunogenicity, showing improved performance over existing methods.

Science Immunology · Feb 14, 2020Peer-reviewedBioinformatics

Overcoming Genetic Drop-outs in Variants-based Lineage Tracing from Single-cell RNA Sequencing Data

Tianshi Lu, Seongoh Park, James J. Zhu, Xiaowei Zhan, Xinlei Wang, Hao Zhu, Tao Wang

This paper develops SClineger, a Bayesian model to correct genetic drop-outs in scRNA-Seq data for accurate lineage tracing across tissues and time scales.

bioRxiv · Jan 1, 2020 · PreprintBioinformatics