Author

Jonathan Carruthers

UK Health Security AgencyORCID 0000-0002-1372-3254Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:clustering· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Thomas FinnieiD· 2 shared Carmen Molina-Parı́siD· 1 shared Grant LytheiD· 1 shared Gustaf WigerbladiD· 1 shared Mariana J. KaplaniD· 1 shared Saumyadipta PyneiD· 1 shared Sumanta RayiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

Thomas FinnieORCID

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2 papers

Recent·Most cited

A mathematical framework for human neutrophil state transitions inferred from single-cell RNA sequence data

Gustaf Wigerblad, Jonathan Carruthers, Sumanta Ray, Thomas Finnie, Grant Lythe, Carmen Molina-Parı́s, Saumyadipta Pyne, Mariana J. Kaplan

The paper develops a mathematical model of human neutrophil maturation using single-cell RNA-seq data, identifying key transition states and rates.

Frontiers in Immunology · Oct 24, 2025Peer-reviewedCell Biology

Using mixture density networks to emulate a stochastic within-host model of Francisella tularensis infection

Jonathan Carruthers, Thomas Finnie

The paper uses mixture density networks to emulate a stochastic within-host model of Francisella tularensis infection, improving parameter estimation and providing estimates of infectious dose and incubation period.

bioRxiv · Jun 15, 2023 · PreprintSystems Biology