A mathematical framework for human neutrophil state transitions inferred from single-cell RNA sequence data
Gustaf Wigerblad, Jonathan Carruthers, Sumanta Ray, Thomas Finnie, Grant Lythe, Carmen Molina-Parı́s, Saumyadipta Pyne, Mariana J. Kaplan
The paper develops a mathematical model of human neutrophil maturation using single-cell RNA-seq data, identifying key transition states and rates.
Frontiers in Immunology · Oct 24, 2025Peer-reviewedCell Biology