Catalytic and inhibitory architecture of comammox ammonia monooxygenase
Zongqiang Li, Tieqiang Mao, Xiaoyun Yang, Zhi-Cong He, Jiawen Yang, Rihui Wu, Kmy Leung, Shengying Li, Ping Han, Wei Peng
This study reports cryo-EM structures of comammox AMO from Nitrospira inopinata and identifies its catalytic and inhibitor-responsive architecture, revealing a methyl-PQ-linked mechanism and stress response to nitrification inhibitors.
bioRxiv · Sep 5, 2026 · PreprintBiophysics