Author

Krithika R. Subramanian

Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-1397-589XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Kashish ChetaliD· 2 shared Nathan SalomonisiD· 2 shared Aishwarya Kulkarni· 1 shared Amit VermaiD· 1 shared Andrew E. Rosselot· 1 shared Ariel Fromowitz· 1 shared Christian I. HongiD· 1 shared Daniel T. StarczynowskiiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Kashish ChetalORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivFeb 4, 2024

Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation

Meenakshi Venkatasubramanian, Leya Schwartz, Nandini Ramachandra…·Nathan Salomonis

The paper identifies a splicing mechanism in AML independent of mutations, showing it drives poor prognosis and can be targeted with PRMT5 inhibition.

DOI 10.1126/scitranslmed.adr1471

humanbulk RNA-seq

Molecular BiologyThe EMBO JournalPeer-reviewedOct 27, 2021

Ontogeny and function of the circadian clock in intestinal organoids

Andrew E. Rosselot, Miri Park, Mari Kim…·Christian I. Hong

This study investigates circadian rhythms in human intestinal organoids, showing circadian phase-dependent necrotic cell death responses to TcdB and identifying anti-phasic gene expression between mouse and human enteroids.

47 citationstop 3%

humanmouse