Author

Meenakshi Venkatasubramanian

Cincinnati Children's Hospital Medical CenterORCID 0009-0001-8673-8692Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Kashish ChetaliD· 2 shared Nathan SalomonisiD· 2 shared Aishwarya Kulkarni· 1 shared Amit VermaiD· 1 shared Ariel Fromowitz· 1 shared Daniel Schnell· 1 shared Daniel T. StarczynowskiiD· 1 shared David ShechteriD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Kashish ChetalORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivFeb 4, 2024

Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation

Meenakshi Venkatasubramanian, Leya Schwartz, Nandini Ramachandra…·Nathan Salomonis

The paper identifies a splicing mechanism in AML independent of mutations, showing it drives poor prognosis and can be targeted with PRMT5 inhibition.

DOI 10.1126/scitranslmed.adr1471

humanbulk RNA-seq

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BioinformaticsBioinformaticsPeer-reviewedMar 19, 2020

Resolving single-cell heterogeneity from hundreds of thousands of cells through sequential hybrid clustering and NMF

Meenakshi Venkatasubramanian, Kashish Chetal, Daniel Schnell…·Nathan Salomonis

The paper introduces an improved clustering algorithm for scRNA-seq data that outperforms existing methods on benchmark datasets and scales to large-scale data.

66 citations

humanscRNA-seq

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