Author

Christian I. Hong

Cincinnati Children's Hospital Medical CenterORCID 0000-0001-8618-8128Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Gang WuiD· 2 shared Toru MatsuuraiD· 2 shared Andrew E. Rosselot· 1 shared Attila Csikász-NagyiD· 1 shared Bence T. Gaizer· 1 shared Choogon LeeiD· 1 shared Danilo E. F. L. FlôresiD· 1 shared Heather A. McCauleyiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Gang WuORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 30, 2026

Circadian clock regulates intestinal epithelial cell differentiation via NOTCH/Hes1 oscillations

Sevde Goker, Sean Suengwon Lee, Bence T. Gaizer…·Christian I. Hong

This study identifies circadian regulation of intestinal epithelial cell differentiation through NOTCH/Hes1 oscillations in mouse enteroids.

1 citation

mousebulk RNA-seq

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NeurosciencebioRxivPreprintOct 1, 2025

Circadian phosphotimer generates time cues through PER dimerization-mediated trans-phosphorylation

Kwangjun Lee, Jiyoung Park, Junghyun Lee…·Choogon Lee

The paper shows that PER dimerization-mediated trans-phosphorylation generates time cues for circadian rhythms, and disrupts it shortens the circadian period and advances sleep cycles in mice.

DOI 10.1101/2025.10.01.679838

mouseexperimental assay

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Molecular BiologyThe EMBO JournalPeer-reviewedOct 27, 2021

Ontogeny and function of the circadian clock in intestinal organoids

Andrew E. Rosselot, Miri Park, Mari Kim…·Christian I. Hong

This study investigates circadian rhythms in human intestinal organoids, showing circadian phase-dependent necrotic cell death responses to TcdB and identifying anti-phasic gene expression between mouse and human enteroids.

47 citationstop 3%

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