Author

Bernhard Steiert

F. Hoffmann-La Roche AGORCID 0000-0002-1398-1624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:statistical model· 2

Frequent Co-Authors

Christian TönsingiD· 1 shared Clemens KreutziD· 1 shared Jens TimmeriD· 1 shared Lena M. Appel· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 3 mutual co-author links

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1 shared paperSystems Biology

Christian TönsingORCID

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2 papers

Recent·Most cited

Systems BiologyThe AAPS JournalPeer-reviewedMar 25, 2026

Theoretical and numerical investigation of the consistency ofmodel comparisons in pharmacometrics

Lena M. Appel, Bernhard Steiert

This paper investigates the consistency of likelihood ratio tests in pharmacometrics by examining the continuity of likelihood functions under parameter fixation in population models.

DOI 10.1208/s12248-026-01227-w

statistical modelbenchmarking

𝕏 PostBluesky

Systems BiologyPLoS Computational BiologyPeer-reviewedSep 22, 2023

Likelihood-ratio test statistic for the finite-sample case in nonlinear ordinary differential equation models

Christian Tönsing, Bernhard Steiert, Jens Timmer, Clemens Kreutz

This paper investigates likelihood-ratio test statistics for nonlinear ODE models in finite-sample settings and finds that corrections are needed to avoid anti-conservative results.

9 citations

statistical modelbenchmarking

𝕏 PostBluesky