Author

Christian Tönsing

University of FreiburgORCID 0000-0003-2822-5191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Jens TimmeriD· 2 shared Bernhard SteiertiD· 1 shared Clemens KreutziD· 1 shared Dantong WangiD· 1 shared Jan HasenaueriD· 1 shared Lena Postawa· 1 shared Leonard SchmiesteriD· 1 shared Lorenz AdlungiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSystems Biology

Jens TimmerORCID

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2 papers

Recent·Most cited

Systems BiologyPLoS Computational BiologyPeer-reviewedSep 22, 2023

Likelihood-ratio test statistic for the finite-sample case in nonlinear ordinary differential equation models

Christian Tönsing, Bernhard Steiert, Jens Timmer, Clemens Kreutz

This paper investigates likelihood-ratio test statistics for nonlinear ODE models in finite-sample settings and finds that corrections are needed to avoid anti-conservative results.

9 citations

statistical modelbenchmarking

𝕏 PostBluesky

Systems BiologyCell ReportsPeer-reviewedAug 1, 2021

Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes define survival threshold in erythroid progenitor cells

Lorenz Adlung, Paul L. Stapor, Christian Tönsing…·Marcel Schilling

The paper models single-cell variability in JAK2/STAT5 signaling and cytoplasmic volume to explain how erythroid progenitor cells transition from binary survival/apoptosis decisions to graded population responses upon Epo stimulation.

21 citations

humanbulk RNA-seq

𝕏 PostBluesky