Author

Clare F. Malone

Broad InstituteORCID 0000-0002-1430-1774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander R. KovachiD· 1 shared Allen Thayakumar BasanthakumariD· 1 shared Anna K. de RegtiD· 1 shared Ara JoiD· 1 shared Assil FahsiD· 1 shared Audrey TailloniD· 1 shared Ben Setter· 1 shared Brian GuedesiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alexander R. KovachORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedJul 14, 2026

CDK8 Inhibition Releases the Muscle Differentiation Block in Fusion-driven Alveolar Rhabdomyosarcoma

Susu Zhang, Kathleen L. Engel, Assil Fahs…·Kimberly Stegmaier

This study identifies CDK8 inhibition as a therapeutic strategy for alveolar rhabdomyosarcoma by inducing myogenic differentiation and impairing tumor growth through a mechanism involving the Mediator kinase module, SAGA complex, and SIX4.

DOI 10.1158/2159-8290.cd-25-1171

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 16, 2026

Proximity-Informed Graph Learning Defines Spatial Protein Communities for Tumor-Associated Proximity Antigen Discovery

Cody Scandore, Clare F. Malone, Christopher K. May…·Olugbeminiyi Fadeyi

The paper develops a proximity mapping workflow to identify tumor-associated antigens by analyzing spatial protein communities and validates a TAA-TAPA pair that enhances tumor cell killing.

DOI 10.64898/2026.02.13.705629

humanspatial transcriptomics

𝕏 PostBluesky