Author

María José Jiménez‐Santos

Spanish National Cancer Research CentreORCID 0000-0002-1430-3067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:scRNA-seq· 2 Approach:deep learning· 1 Approach:machine learning (classical)· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Santiago García‐MartíniD· 3 shared Fátima Al‐ShahrouriD· 2 shared Gonzalo Goméz-LópeziD· 2 shared Carlos Carretero-PucheiD· 1 shared Cemsel BafligiliD· 1 shared Coral Fustero TorreiD· 1 shared Cristina Fernández MolinaiD· 1 shared Ioanna TiniakouiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Santiago García‐MartínORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintDec 12, 2025

Beyond one-size-fits-all: single-cell transcriptomic signatures predict drug efficacy and reveal responder subgroups in endometriosis

Raúl Pérez-Moraga, Cemsel Bafligil, Sarah Louise Harden…·Cristina Fernández Molina

This paper uses single-cell transcriptomics to identify drug response subgroups and therapeutic targets in endometriosis, revealing tissue-specific and inter-patient heterogeneity.

DOI 10.64898/2025.12.09.693218

humanscRNA-seq

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Cancer BiologyNAR CancerPeer-reviewedOct 3, 2024

Spatial Transcriptomics in Breast Cancer Reveals Tumour Microenvironment-Driven Drug Responses and Clonal Therapeutic Heterogeneity

María José Jiménez‐Santos, Santiago García‐Martín, Marcos Rubio‐Fernández…·Fátima Al‐Shahrour

This study uses spatial transcriptomics to analyze drug responses in breast cancer tumors and identifies therapeutic heterogeneity linked to tumor location and microenvironment.

35 citationstop 4%

humanspatial transcriptomics

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BioinformaticsGenome MedicinePeer-reviewedDec 1, 2021

Beyondcell: targeting cancer therapeutic heterogeneity in single-cell RNA-seq

Coral Fustero Torre, María José Jiménez‐Santos, Santiago García‐Martín…·Fátima Al‐Shahrour

Beyondcell identifies drug-responsive subpopulations in single-cell RNA-seq data and proposes cancer-specific treatments by analyzing therapeutic clusters and differential drug sensitivity.

130 citationstop 2%

humanscRNA-seq

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