Author

Ryan M. Ames

University of ExeterORCID 0000-0002-1432-5629Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:machine learning (classical)· 2 Approach:statistical model· 2 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Akshay BhingeiD· 1 shared Alessandro RosaiD· 1 shared Anjana Magaji-UmashankariD· 1 shared Carlos Bayón· 1 shared Craig R. G. WillisiD· 1 shared Erika KrolliD· 1 shared Fabrizio CostaiD· 1 shared Graham ThomasiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperGenomics

Akshay BhingeORCID

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3 papers

Recent·Most cited

Plant BiologyPLoS PathogensPeer-reviewedJan 9, 2025

A conserved fungal Knr4/Smi1 protein is vital for maintaining cell wall integrity and host plant pathogenesis

Erika Kroll, Carlos Bayón, J. J. Rudd…·Kim Elizabeth Hammond-Kosack

This study identifies FgKnr4 as a conserved fungal protein critical for cell wall integrity and pathogenicity, validated through network analysis and functional studies in Fusarium graminearum and Zymoseptoria tritici.

6 citations

bulk RNA-seqstatistical model

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BioinformaticsbioRxivPreprintSep 26, 2023

Fungal Pathogen Gene Selection for Predicting the Onset of Infection Using a Multi-Stage Machine Learning Approach

Graham Thomas, Oliver Stoner, Fabrizio Costa, Ryan M. Ames

This study uses machine learning to identify genes predicting infection onset in the fungal pathogen Zymoseptoria tritici using transcriptomics data.

1 citation

fungi (other)bulk RNA-seq

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GenomicsbioRxivPreprintMar 9, 2021

Single cell transcriptomics identifies master regulators of dysfunctional pathways in SOD1 ALS motor neurons

Seema Chandramohan Namboori, Patricia Thomas, Ryan M. Ames…·Akshay Bhinge

The paper uses single cell transcriptomics to identify master regulators of dysfunctional pathways in SOD1 ALS motor neurons, finding SMAD2 activation as a key driver of neurodegeneration.

3 citations

humanscRNA-seq

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