Author

Craig R. G. Willis

University of ExeterORCID 0009-0002-0433-2144Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Abhijit SukuliD· 1 shared Akshay BhingeiD· 1 shared Alessandro RosaiD· 1 shared Ana TeixeiraiD· 1 shared Anna E. Miller· 1 shared Anupama BinoyiD· 1 shared Austin M. BrowniD· 1 shared Birgit SchillingiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Abhijit SukulORCID

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4 papers

Recent·Most cited

Mitochondrial priming in human germ cell tumors is dependent on MCL1 and BCL2L1

Sirli Anniko, Sonia Khan, Jamie RJ Morton, Wajiha Iftikhar, Ana Teixeira, Craig R. G. Willis, Kirsten Riches‐Suman, Krzysztof Poterlowicz, Steven D. Shnyder, Rod Thomas Mitchell, Sherif F. El‐Khamisy, Simon J. Allison, Peter K. Nicholls

This study identifies MCL1 and BCL2L1 as critical for GCT survival and shows their inhibition enhances response to DNA damaging agents.

bioRxiv · Sep 26, 2026 · PreprintCancer Biology

Chronic alcohol intake elicits distinct multi-omic profiles in the liver versus skeletal muscle of mice

Craig R. G. Willis, Muni Swamy Ganjayi, Austin M. Brown, Samantha E. Moser, Nathaniel J. Szewczyk, Brian C. Clark, Cory W. Baumann

This study identifies distinct multi-omic profiles in liver and skeletal muscle of mice under chronic alcohol exposure, revealing tissue-specific molecular responses and potential therapeutic targets.

Alcoholism Clinical and Experimental Research · Jan 30, 2026Peer-reviewedBioinformatics

Sirt5 regulates chondrocyte metabolism and osteoarthritis development through protein lysine malonylation

Huanhuan Liu, Anupama Binoy, Siqi Ren, T. C. Martino, Anna E. Miller, Craig R. G. Willis, Shivakumar R. Veerabhadraiah, Abhijit Sukul, Joanna Bons, Jacob Rose, Birgit Schilling, Michael J. Jurynec, Shouan Zhu

This study identifies Sirt5's role in regulating chondrocyte metabolism and osteoarthritis through lysine malonylation, showing its dysregulation contributes to OA in aging and obesity.

Arthritis & Rheumatology · Apr 3, 2025Peer-reviewedCell Biology

Single cell transcriptomics identifies master regulators of dysfunctional pathways in SOD1 ALS motor neurons

Seema Chandramohan Namboori, Patricia Thomas, Ryan M. Ames, Sophie Hawkins, Lawrence O. Garrett, Craig R. G. Willis, Alessandro Rosa, Lawrence Walter Stanton, Akshay Bhinge

The paper uses single cell transcriptomics to identify master regulators of dysfunctional pathways in SOD1 ALS motor neurons, finding SMAD2 activation as a key driver of neurodegeneration.

bioRxiv · Mar 9, 2021 · PreprintGenomics