Lingxue Zhu

This study examines the role of noncoding variation in autism spectrum disorder using whole genome sequencing of 2,076 genomes, finding no significant association after correction for multiple testing.

SOUP, a semi-soft clustering method, identifies pure and transitional cell types from single-cell gene expression data by first detecting pure cells and then estimating membership matrices.

This paper introduces a unified statistical model for single cell and bulk RNA-seq data that improves dropout correction and cell type deconvolution.