Zainalabedin Samadi

Reconstructing signaling history of single cells with imaging-based molecular recording

This paper introduces INSCRIBE, a method to reconstruct single-cell signaling history using imaging, and finds that BMP pathway response is heritable across cell divisions.

Spatial motifs reveal patterns in cellular architecture of complex tissues

The paper introduces a method to detect spatial motifs in tissue maps, revealing previously unrecognized patterns in cell type arrangements in mouse neural tissues.