Maria Victoria Puig

A Reproducible Cortical Model of Focal Epileptiform Activity with a Multi-Biomarker Analysis Pipeline

This paper develops an acute cortical model of focal epileptiform activity in mice and introduces a multi-biomarker analysis pipeline to characterize the induced activity.

Cellular mechanisms underlying the pro-cognitive effects of serotonin 5-HT7 receptors in a mouse model of schizophrenia

This study investigates how 5-HT7 receptors modulate hippocampal-prefrontal circuits in schizophrenia models, finding that their blockade improves cognitive and emotional symptoms.

Neural substrates of cognitive impairment in a NMDAR hypofunction mouse model of schizophrenia and rescue by risperidone

This study investigates the neural mechanisms of cognitive impairment in a schizophrenia mouse model and shows that risperidone rescues memory and auditory perception deficits by restoring mPFC-dHPC connectivity.

Postnatal environmental enrichment enhances memory by shaping hippocampal-prefrontal theta and gamma rhythms in diploid and trisomic female mice

Phencyclidine-induced psychosis causes hypersynchronization and disruption of connectivity within prefrontal-hippocampal circuits that is rescued by antipsychotic drugs

This study examines how phencyclidine-induced psychosis disrupts prefrontal-hippocampal neural synchrony and connectivity, and how antipsychotic drugs reverse these effects.