Author

Demetrio Julián Santiago

Spanish National Centre for Cardiovascular ResearchORCID 0000-0002-1541-8034Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anselmo CancianiiD· 1 shared Chiara Di AntonioiD· 1 shared Chiara MarabelliiD· 1 shared Emanuele Pirana· 1 shared Federico FornerisiD· 1 shared Martino BolognesiiD· 1 shared Silvia Giuliana PrioriiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Anselmo CancianiORCID

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1 paper

Recent·Most cited

Cardiac Calsequestrin is a Physiological Dimer that Polymerizes through a Ca2+-Triggered Cooperative Switch

Chiara Marabelli, Demetrio Julián Santiago, Emanuele Pirana, Chiara Di Antonio, Anselmo Canciani, Martino Bolognesi, Federico Forneris, Silvia Giuliana Priori

This study shows cardiac Calsequestrin (CASQ2) is an intrinsic dimer that polymerizes via a Ca2+-triggered cooperative switch, with K+ ions modulating this process.

bioRxiv · Apr 7, 2026 · PreprintBiochemistry