Amyloid β interaction with membranes: Removal of cholesterol from the membranes to catalyze aggregation and amyloid pathology
Rishiram Baral, Ruan van Deventer, Yuri L. Lyubchenko
This study shows that Aβ42 removes cholesterol from membranes, accelerating its aggregation and contributing to Alzheimer's disease pathology.
bioRxiv · Aug 20, 2025 · PreprintBiophysics