Author

Brian F.P. Edwards

Wayne State UniversityORCID 0000-0002-1571-2866Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Benjamin L. KidderiD· 1 shared Kalel Garrett· 1 shared Varshika Ram Prakash· 1 shared Yusuf Najy· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBioinformatics

Benjamin L. KidderORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintOct 22, 2025

De novo protein design enables targeting of intractable oncogenic interfaces

Varshika Ram Prakash, Yusuf Najy, Kalel Garrett…·Benjamin L. Kidder

This paper introduces DesignForge, a de novo protein design framework that creates therapeutic protein binders targeting oncogenic PPIs, showing high structural confidence and hotspot engagement.

DOI 10.1101/2025.10.22.683953

protein structuredeep learning

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