Therapeutic effects of PDGF-AB/BB against cellular senescence in human intervertebral disc
Changli Zhang, Martha Elena Díaz‐Hernández, Takanori Fukunaga, Sreekala P.V. Shenoy, Sangwook Tim Yoon, Lisbet Haglund, Hicham Drissi
This study shows that PDGF-AB/BB treatment reduces senescence in human intervertebral disc cells by modulating gene expression related to cell cycle, metabolism, and oxidative stress.
eLife · Jul 16, 2025Peer-reviewedCell Biology