Astrocyte-selective AAV-ADAMTS4 gene therapy combined with hindlimb rehabilitation promotes functional recovery after spinal cord injury
Jarred M. Griffin, Barbara Fackelmeier, Connor A. Clemett, Dahna M. Fong, Alexandre Mouravlev, Deborah Young, Simon J. O’Carroll
This study combines AAV-ADAMTS4 gene therapy with hindlimb rehabilitation to enhance functional recovery after spinal cord injury by degrading CSPGs.
Experimental Neurology · Feb 7, 2020Peer-reviewedNeuroscience