Author

Rachel M. Koldej

The Royal Melbourne HospitalORCID 0000-0002-1627-8934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

Andreas StrasseriD· 1 shared Andrew Warwick RobertsiD· 1 shared Annika PochiD· 1 shared Charis E. TehiD· 1 shared Charlotte A. SladeiD· 1 shared Constantine Si Lun TamiD· 1 shared Damien G. HicksiD· 1 shared Daniel H.D. GrayiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andreas StrasserORCID

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1 paper

Recent·Most cited

Early cytokine-driven adaptation of survival pathways in lymphoid cells during targeted therapies

Meng-Xiao Luo, Tania Tan, Marie Trussart, Annika Poch, Minh-Hanh Thi Nguyen, Terence Paul Speed, Damien G. Hicks, Esther Bandala‐Sanchez, Hongke Peng, Stéphane Chappaz, Charlotte A. Slade, Daniel T. Utzschneider, Rachel M. Koldej, David Ritchie, Andreas Strasser, , Daniel H.D. Gray

This study shows that CLL cells rapidly adapt to venetoclax by upregulating pro-survival proteins and cytokines, suggesting combination therapies targeting these pathways could improve treatment outcomes.

Blood · Oct 29, 2024Peer-reviewedCancer Biology