Analyses of rare and common alleles in parent-proband trios implicate rare missense variants in SLC6A1 in schizophrenia and confirm the involvement of loss of function intolerant and neurodevelopmental disorder genes.
Elliott Rees, Jun Han, Joanne Morgan, Noa Carrera, Valentina Escott‐Price, Andrew J. Pocklington, Madeleine Duffield, Lynsey S. Hall, Sophie E. Legge, Antonio F. Pardiñas, Alexander L. Richards, Julian Roth, Tatyana Lezheiko, Nikolay V. Kondratyev, Вера Евгеньевна Голимбет, , Michael John Owen
The paper analyzes rare and common alleles in schizophrenia trios, identifying rare missense variants in SLC6A1 and confirming the role of neurodevelopmental disorder genes.
bioRxiv · Apr 18, 2019 · PreprintGenetics