Author

Elias Allara

University of CambridgeORCID 0000-0002-1634-8330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genetics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:GWAS / association mapping· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:GWAS summary statistics· 2 Research Focus:variant effect prediction· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Adam S. ButterworthiD· 3 shared John DaneshiD· 3 shared Clare Oliver‐WilliamsiD· 2 shared Emanuele Di AngelantonioiD· 2 shared Johannes KettuneniD· 2 shared Marjo‐Riitta JärveliniD· 2 shared Markus PerolaiD· 2 shared Mika A. P. KähöneniD· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Adam S. ButterworthORCID

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4 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintOct 20, 2022

Genome-wide characterization of circulating metabolic biomarkers reveals substantial pleiotropy and novel disease pathways

Minna K. Karjalainen, Savita Karthikeyan, Clare Oliver‐Williams…·Johannes Kettunen

This study identifies 400+ genetic loci associated with circulating metabolic traits and highlights pleiotropy and novel disease pathways.

3 citations

humanmetabolomics

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Genetic & Genomic MedicineNature AgingPeer-reviewedFeb 17, 2022

A major population resource of 474,074 participants in UK Biobank to investigate determinants and biomedical consequences of leukocyte telomere length.

Veryan Codd, Matthew J. Denniff, Chloe Elizabeth Swinfield…·Nilesh J. Samani

The paper reports LTL measurements in 474,074 UK Biobank participants, identifying factors like age, sex, ethnicity, and white cell count associated with LTL variation.

249 citationstop 1%

humanGWAS summary statistics

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GeneticsPLoS BiologyPeer-reviewedDec 20, 2019

Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

Johannes Kettunen, Michael Vaclav Holmes, Elias Allara…·Mika Ala‐Korpela

The paper examines the effects of CETP and HMGCR genetic inhibition on lipoprotein profiles and CHD risk, finding distinct impacts on cholesterol and triglyceride compositions.

47 citationstop 1%

humanbulk RNA-seq

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GeneticsbioRxivPreprintMar 4, 2019

A robust and efficient method for Mendelian randomization with hundreds of genetic variants: unravelling mechanisms linking HDL-cholesterol and coronary heart disease

Stephen Burgess, Christopher N. Foley, Elias Allara…·Joanna M. M. Howson

This paper introduces a robust MR method that identifies groups of genetic variants with similar causal effects, showing it outperforms existing methods in accuracy and speed for HDL-cholesterol and CHD analysis.

13 citations

GWAS summary statisticsstatistical model

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