BioinformaticsbioRxivPreprint
eTRex Reveals Oncogenic Transcriptional Regulatory Programs Across Human Cancers
Zeyu Lu, Yuqiu Yang, Qiang Zheng…·Xinlei Wang
The paper develops eTRex, a variational Bayesian model, to analyze 4,819 ATAC-seq datasets and create a pan-cancer atlas of transcriptional regulator profiles, revealing common and context-specific regulators.