Benjamin J. van Soldt

This paper identifies KLHDC7B as a gene associated with age-related hearing loss in humans and validates its role in hearing maintenance using two mouse models.

The paper uses single-cell multimodal analyses to show how maternal diabetes alters epigenomic and transcriptomic states in cardiac and craniofacial progenitors, leading to developmental defects.

The paper uses single-cell epigenomics and machine learning to model cell-cell communication networks in cardiac development and identify dysregulation in TBX1 deletion.