Author

Pascale Kropf

Imperial College LondonORCID 0000-0002-1670-8332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Emebet Adem· 4 shared Endalew YizengawiD· 4 shared Yegnasew TakeleiD· 4 shared Edward Cruz CerveraiD· 3 shared Ingrid MülleriD· 3 shared James Anthony CottoniD· 3 shared Endalkachew NibretiD· 2 shared Abaineh MunsheaiD· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Emebet Adem

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Different isolates of Leishmania aethiopica elicit distinct effector functions in primary human monocytes

Edward Cruz Cervera, Emebet Adem, Endalew Yizengaw, Yegnasew Takele, Ingrid Müller, James Anthony Cotton, Pascale Kropf

This study shows that different Leishmania aethiopica isolates trigger distinct effector responses in human monocytes, with long-term cultured parasites eliciting different outcomes than recently isolated ones.

bioRxiv · Feb 26, 2025 · PreprintImmunology

Distinct neutrophil effector functions in response to different isolates of Leishmania aethiopica

Emebet Adem, Edward Cruz Cervera, Endalew Yizengaw, Yegnasew Takele, S. Shorter, James Anthony Cotton, Giulia T. M. Getti, Pascale Kropf

The paper investigates how different Leishmania aethiopica isolates affect neutrophil effector functions in vitro, finding that long-term cultured isolates induce more ROS production and distinct neutrophil populations.

Parasites & Vectors · Nov 11, 2024Peer-reviewedImmunology

Altered co-stimulatory and inhibitory receptors on monocyte subsets in patients with visceral leishmaniasis

Emebet Adem, Endalew Yizengaw, Tadele Mulaw, Endalkachew Nibret, Ingrid Müller, Yegnasew Takele, Pascale Kropf

This study examines changes in co-stimulatory and inhibitory receptors on monocyte subsets in visceral leishmaniasis patients before and after treatment.

PLoS neglected tropical diseases · Aug 19, 2024Peer-reviewedImmunology

Parasite genetic variation and systemic immune responses are not associated with different clinical presentations of cutaneous leishmaniasis caused by Leishmania aethiopica

Endalew Yizengaw, Yegnasew Takele, Susanne Ursula Franssen, Bizuayehu Gashaw, Mulat Yimer, Emebet Adem, Endalkachew Nibret, Gizachew Yismaw, Edward Cruz Cervera, Kefale Ejigu, Dessalegn Tamiru, Abaineh Munshea, Ingrid Müller, Richard Weller, James Anthony Cotton, Pascale Kropf

This study investigates whether parasite genetic variation or immune responses differ among clinical presentations of cutaneous leishmaniasis caused by Leishmania aethiopica, finding no significant associations.

bioRxiv · Apr 19, 2024 · PreprintGenomics