Complex interplay between gene deletions and the environment uncovers cellular roles for genes of unknown function in Escherichia coli
Kaat Sondervorst, Kristina Nešporová, Matthew Herdman, Bart Steemans, Joëlle Rosseels, Sander K. Govers
The paper uses cross-condition image-based profiling of E. coli deletion strains to identify five genes of unknown function and characterize their cellular roles through phylogenetic, structural, and localization analysis.
mSystems · Jun 10, 2025Peer-reviewedMicrobiology