Author

Bruce M. McManus

University of British ColumbiaORCID 0000-0002-1685-2529Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Scott J. TebbuttiD· 3 shared Amrit SinghiD· 2 shared Raymond T. NgiD· 2 shared Virginia CheniD· 2 shared Zsuzsanna HollanderiD· 2 shared Bradley Williams· 1 shared Casey P. ShannoniD· 1 shared Darlene L. Y. DaiiD· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBioinformatics

Scott J. TebbuttORCID

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3 papers

Recent·Most cited

Circulating miR-4532 is associated with loss of ambulation in dysferlinopathy

Tajveer Singh Grewal, Zsuzsanna Hollander, Darlene L. Y. Dai, Virginia Chen, Hillarie Plessner Windish, Douglas E. Albrecht, Elaine Lee Paoliello, Laura Rufibach, Bradley Williams, Plavi Mittal, Sara Assadian, Janet E Wilson-McManus, Bruce M. McManus, Raymond T. Ng, Scott J. Tebbutt, , Amrit Singh

The paper identifies miR-4532 as a circulating miRNA associated with ambulatory status in dysferlinopathy, showing differential expression between ambulatory and non-ambulatory patients.

bioRxiv · Jan 6, 2026 · PreprintBioinformatics

Omics BioAnalytics: Reproducible Research using R Shiny and Alexa

Amrit Singh, Scott J. Tebbutt, Bruce M. McManus

The paper introduces a web framework for omics data analysis using R Shiny and Amazon Alexa, enabling interactive exploration and hypothesis generation for health and disease biomarkers.

bioRxiv · May 5, 2020 · PreprintBioinformatics

A novel approach to identifying marker genes and estimating the cellular composition of whole blood from gene expression profiles

Casey P. Shannon, Robert Balshaw, Virginia Chen, Zsuzsanna Hollander, Mustafa Toma, Bruce M. McManus, J. Mark Fitzgerald, Don D. Sin, Raymond T. Ng, Scott J. Tebbutt

This paper introduces a multi-response Gaussian model to predict peripheral whole blood composition from Affymetrix Gene ST expression profiles, outperforming existing methods on this platform.

bioRxiv · Feb 3, 2016Bioinformatics