Zhiyuan Hu

RegVelo integrates gene regulatory networks with dynamic modeling to predict cellular changes and perturbations, showing improved performance in cell cycle, hematopoiesis, and pancreatic development datasets.

The paper identifies gene regulatory circuits controlling cranial neural crest migration and plasticity using multi-omics and computational methods.

The paper identifies a WNT7A-FZD5 signaling axis critical for human fallopian tube stem cell self-renewal using single-cell transcriptomics and organoid models.

CIDER is a meta-clustering framework that improves scRNA-Seq data integration and evaluation by outperforming existing methods in simulated and real datasets without requiring prior cellular annotations.