Development of a Bacterial Colorimetric Reporter System for Functional Screening of SARS-Cov-2 Main Protease Inhibitors Using Plant Preparations (juices): A Proof-of-Concept Study
Shaza S. Issa, Andrew А. Zelinsky, Haidar J. Fayoud, Roman R. Zhidkin, Tatiana V. Matveeva
The paper develops a bacterial colorimetric reporter system to screen SARS-CoV-2 Mpro inhibitors using plant juices, showing it can detect inhibition in living cells.
bioRxiv · Dec 15, 2025 · PreprintMolecular Biology